One of numerous versions of this theme painted by Titian and his workshop in the 1550s, this Mater Dolorosa with clasped hands is particularly impressive because of the delicate colour scheme of the blue cloak, pink garment, and saffron yellow veil. Inventories tell us that Charles V also took a Madonna on wood, together with the Ecce Homo, with him to the monastery of Yuste. Some authors assume that this is the work in question.