Judith and Holofernes is a part of the Sistine Chapel ceiling painting by the Italian master artist Michelangelo. The account of Judith's beheading Holofernes has been treated by several painters and sculptors. Michelangelo depicts the scene in multiple aspects in one of the Pendentives, or four spandrels on the ceiling of the Sistine Chapel. The Sistine Chapel ceiling, painted by Michelangelo between 1508 and 1512, is one of the most renowned artworks of the High Renaissance.